At Eurocrypt '02 Cramer and Shoup proposed a general paradigm to construct practical public-key cryptosystems secure against the adaptive chosen ciphertext attack as well as several concrete examples.Using the construction, we present a new variant of the Cramer-Shoup encryption scheme, which is secure against the adaptive chosen ciphertext attack. Our variant is based on the problem related to the quadratic residuosity (QR). In, they also proposed the encryption scheme based on the QR, but this scheme is less efficient than those based on the decision Diffie-Hellman problem or the decision composite residuosity. In this paper, we define the new assumptions related to the QR assumption and propose a new public-key encryption scheme whose security is based on the new assumption. Our scheme is more efficient than the QR-based scheme proposed by Cramer and Shoup.